Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year.

The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence. Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel.

About the position
We announce a three-year research position in the CRISPR gene therapy group led by Emma Haapaniemi to be based at NCMM, University of Oslo & Oslo University Hospital. We welcome applications both from recent PhD graduates (postdoctoral fellow position) and more experienced scientists (researcher position).
The aim of the Haapaniemi group (www.haapaniemilab.org) is to build a gene editing platform that can be used to correct patient-specific mutations in ex vivo cell therapies for genetic immune and other rare childhood diseases. We use high-throughput biology techniques to optimize, develop and understand the CRISPR-Cas9 system that forms the base of the platform, and develop and implement methods to evaluate its safety in a clinical setting. We will use the gene editing technologies for the benefit of the patients in the Nordic hospitals.

Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway, and has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

Kvalifikasjoner:

• PhD, BA or MA (expected PhD graduation date within 6 months of application closing date)
  
• At least one published first-author paper
  
• Fluent oral and written English communication skills

The following qualifications will count in the assessment of the applicants:

• Documented experience in (hematopoietic) stem cell research
  
• Experience with any of the following techniques: multi-color flow cytometry, Next Generation Sequencing library preparation, immune cell culture and transfection,
• CRISPR editing in primary cells, or experience with human-mouse xenotransplants.
  
• Experience in genetic analyses
  
• Ability to communicate and work in shared multidisciplinary projects
  
• Experience in student supervision

Personlige egenskaper:

• Communications and interpersonal skills
• Adaptability and flexibility
• Highly motivated
  
• Goal-oriented
  
• Well-structured
  
• Thorough
  
• Creative
  
• Contribute to a good working environment
  
• Good communication skills
  
• High work capacity
  
• Strong work ethics

Vi tilbyr:

• Salary per annum depends on qualifications in a position as a postdoctoral research fellow (recent PhD graduates) or researcher (experienced applicants)
  
• An exciting, translational project where your strong basic science background can directly benefit our sickest patients
  
• Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

 

How to apply
The application must include:

• Cover letter (statement of motivation, summarizing scientific work and research interest)
  
• CV (summarizing education, positions, pedagogical or administrative experience and other qualifying activity)
  
• Copies of educational certificates (academic transcripts only)
  
• List of publications
  
• List of 3 reference persons (name, relation to candidate, e-mail and phone number). Please list both previous supervisors, peers (fellow postdocs/PhD students) and
• students that you have supervised.

Please deliver the application with attachments in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English.

In assessing the applications, special emphasis will be placed on the documented, academic qualifications as well as the candidate’s motivation and personal suitability. We will arrange interviews with the best qualified candidates. We expect that the successful candidate will be able to complete the project during the period of employment.

Formal regulations
According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

The appointment may be shortened/given a more limited scope within the framework of the applicable guidelines on account of any previous employment in academic positions.

Oslo University Hospital has an agreement for all employees, aiming to secure rights to research results etc.

Contact information
Inquiries about the positions can be directed to group leader Dr. Emma Haapaniemi, emma.haapaniemi@ncmm.uio.no