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Helse Sør-øst RHF
A post-doc position is available in the Cancer Molecular Medicine group of Dr. Enserink at the Institute for Cancer Research at the Division for Cancer Medicine from September 01, 2022 for 3 years (the start date can be negotiated).
The organization and research focus
The Cancer Molecular Medicine group is located at the Radium hospital, which is part of Oslo University Hospital, the largest academic hospital in Scandinavia. The group is a member of a Norwegian Centre of Excellence (Centre for Cancer Cell Reprogramming, CanCell), which consists of six research groups focused on unraveling molecular mechanisms of tumorigenesis. One of the main research aims of the group is to better understand the cellular response to nutrient starvation, particularly autophagy. Autophagy is a powerful catabolic process that must be carefully regulated, because uncontrolled autophagy can result in severe fitness defects. Although much is known about the core autophagy machinery, it remains poorly understood how the cell regulates the kinetics of this process under fluctuating nutrient conditions.
During the past years we have determined the effect of nearly every gene in the budding yeast genome on autophagy kinetics. These unpublished findings suggest the existence of intricate feedback loops and adaptive mechanisms that control commitment to autophagy and that fine-tune autophagic input during nutrient starvation. This project will focus on unraveling these regulatory pathways with particular focus on newly identified networks that control commitment and noise suppression in the autophagy pathway.
The group is located at the Radium hospital campus of Oslo University Hospital. Norway is consistently ranked as one of the places in the world to live in.
Oslo University Hospital is a workplace with great diversity. We believe this is essential to perform the tasks required of us. Therefore, we pursue diversity among our job applicants and encourage everyone to apply regardless of who you are and what background you have.
We are looking for a talented, enthusiastic and determined person who can work both independently as well as in the context of a team. Potential candidates have completed (or are very close to completing) a PhD degree in biology. The successful candidate is positive-minded, is looking forward to learning new techniques, has good communication skills and is well organized. Experience with gene expression analysis, bioinformatics and molecular biology is important. Additional in-depth knowledge of autophagy, yeast genetics or mathematics (machine learning, neural networks) is a strong advantage.
How to apply
Interested persons should submit the following documents to Webcruiter (not by email)
(note that applications lacking any of these three requirements will be discarded automatically, and only applications in Webcruiter will be evaluated):
A concise application letter (1-2 pages) describing why you are the best candidate for this position.
Curriculum vitae, including a list of publications (manuscripts on BioRxiv can be included)
Three reference letters, including contact information of all the references (email address, postal address, phone number and relation to candidate).
The application with attachments
must be delivered in our electronic recruiting system, please follow the link “apply for position". Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language). In assessing the applications, special emphasis will be placed on the documented academic qualifications, as well as the candidate’s motivation and personal suitability. Interviews with the best qualified candidates will be arranged.
It is expected that the
successful candidate will be able to complete the project in the course of the period of employment.
- Strong teamwork skills
- Analytical and critical thinking
- Ability to work independently and take initiatives
- A dynamic and exciting research theme in a positive, collaboration-minded research team with excellent opportunities for further academic development.
- A research environment with state of the art core facilities and excellent international network
- Full-time three-year position.
- Attractive salary as stipulated by the guidelines from Oslo University Hospital.
- Flexible work hours.