A three-year PhD Research Fellowship is available at the Section for Cancer Cytogenetics, Department of Pathology, Oslo University Hospital, Norway.

The successful candidate will join an active and internationally recognized research environment focusing on cancer genomics and transcriptomics. The project will involve translational research aimed at improving our understanding of the genetic mechanisms underlying cancer development and progression.
The PhD candidate will work in close collaboration with clinicians, molecular biologists, and bioinformaticians and will have access to state-of-the-art technologies and research infrastructure. The candidate for this position will join an existing experienced group with established expertise in cancer genetics and cytogenetics and will have the opportunity to work collaboratively across multiple cancer forms in the field of solid tumors (mostly sarcomas).

The PhD project focuses on investigating the cellular and molecular heterogeneity of soft tissue sarcomas (STS), a rare and diverse group of malignant tumors originating from mesenchymal tissue. The aim of the project is to identify prognostic and predictive biomarkers using the latest advanced technique, spatial transcriptomics, in combination with genomics, transcriptomics, proteomics and histology at the single-cell level. The focus is on mapping spatial heterogeneity, both within individual tumors and across tumors from different patients, to improve classification and treatment strategies for STS. The goal is to develop a more precise, molecularly informed subclassification system that can support personalized treatment, similar to approaches already implemented for certain leukemias and other sarcomas.

The Section for Cancer Cytogenetics performs advanced cancer cytogenetic diagnostics analyzing neoplasia-specific genome abnormalities in cancer cells, in addition to performing research in biomedicine to gain new knowledge that can contribute to better patient care. We are looking for a motivated and results-oriented PhD student for a three years scholarship financed by the South East Regional Health (Helse Sør Øst).

Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and we encourage all qualified candidates, regardless of background, to apply!

Kvalifikasjoner:

Applicants must have:

• A master’s degree in molecular biology, genetics, or biotechnology (before the start of the program/registration to the University of Oslo).
• A solid academic and practical background in cancer biology, genomics, transcriptomics, proteomics, and molecular biology with documented results.
• Experience with molecular biology techniques - hands on bench.
• Knowledge of bioinformatics and/or genomic/transcriptomic/proteomic data analysis is desirable.
• Familiarity with statistical and computational approaches for biological data analysis is considered beneficial.
• Good written and oral communication skills in English.
• Ability to work independently as well as collaboratively in an international and interdisciplinary research environment.
• Strong motivation for scientific research, critical thinking, and academic development.
• Applicants who are in the final stage of their Master’s degree are also encouraged to apply, provided that all degree requirements, including the thesis defense, are completed before commencement of the position.

Personlige egenskaper:

• Contributes positively to an inclusive and supportive work environment by valuing diverse perspectives and engaging respectfully with colleagues.
• Demonstrates strong organizational skills and the ability to prioritize tasks effectively in a dynamic research setting.
• Is open to feedback and committed to continuous learning and professional development.
• Shows integrity and responsibility in conducting research, handling data, and collaborating with team members.
• Thrives in an interdisciplinary and international environment, appreciating collaboration across different scientific backgrounds and cultures.

Documentation of previous education and experience must be attached to the application, which is sent via webcruiter by clicking on the link "apply for the position"

Vi tilbyr:

• An exciting and stimulating research environment.
• Access to modern laboratory facilities and advanced technologies.
• Opportunities for international collaboration and scientific networking.
• Exciting work within a field that is constantly developing and of increasing importance.
• Salary according to institutional regulations and qualifications.
• A full-time position for three years.