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Postdoc: Epigenetic and epitranscriptomic regulation in oocytes and embryos, and in cancer

Offentlig forvaltning

Oslo University Hospital is Norway's largest hospital with more than 20,000 employees, and is a major contributor to biomedical research.

A three-year postdoctoral fellowship on oocyte and embryo epigenetics and epitranscriptomics is now available in the Dahl research group. We are seeking highly motivated postdoctoral research fellows to lead this work. Situated at the Oslo University Hospital, the Dahl Laboratory is well positioned for conducting both basic and translational research using mouse and patient material. Some projects in the lab focus on the epigenetic reprogramming of oocyte development and its significance for mammalian and human reproduction and for fertility preservation. An overarching theme is the understanding of mechanisms and epigenetic/epitranscriptomic information in the passing of life from one generation to the next, building on our recent discoveries (Dahl et al., Nature 2016; Sankar et al., Nat. Cell Biol. 2020; Wang et al., Nat Struct Mol Biol. 2023; Li et al., Nat Biotechnol. 2023). Furthermore, we have several projects focusing on epigenetics in aging and cancer.

Oslo University Hospital is a workplace with great diversity. We believe this is absolutely crucial to solving the tasks required of us. We therefore want this diversity to be reflected among the applicants for our positions and encourage everyone to apply regardless of who you are and what background you have.

Kvalifikasjoner:

  • A strong background in Molecular Biology and Cell Biology
  • Knowledge of methods in molecular biology is essential, as well as experience with one or more of the following research areas and techniques: Epigenetics, oogenesis, embryology, gametogenesis, ChIP-seq, WGBS, CRISPR/Cas9, Mass Spec, collection of mouse and human oocytes and embryos, injections and/or other manipulation of oocytes/embryos, FACS sorting, immunofluorescence microscopy, single-cell technologies and bioinformatics.
  • A deep understanding of epigenetics will be considered an advantage. Good knowledge of oocyte/embryo biology will be considered an advantage.
  • Potential candidates have completed a PhD degree. Previous postdoc experience is considered an advantage.
  • License in Laboratory Animal Handling is considered an advantage.
  • Excellent English written and verbal communication skills are required.

Education field
Molecular Biology, Cell Biology, Biochemistry, Bioinformatics/genomics or computer science, or similar fields.

Education level
PhD degree in Molecular Biology, Cell Biology, Biochemistry, Bioinformatics/genomics or computer science, or similar fields, with one or more publications in internationally well-renowned, peer-reviewed scientific journals.

Personlige egenskaper:

The candidate should be highly motivated and dedicated, and have a strong interest in scientific research. The candidate should be able to work both independently as well as in the context of a team, and be well organized. Good communication skills are an advantage as the successful applicant is expected to interact well with computational biologists, clinicians, embryologists and other members of the lab.

    Vi tilbyr:

    • An ambitious and stimulating scientific environment with excellent opportunities for academic development
    • Three-year position with the possibility of exention
    • Top modern and excellent lab facilities with a wide range of core facilities
    • Attractive salary according to the guidelines from the Oslo University Hospital
    • Favorable pension arrangements
    • Attractive welfare arrangements, with affordable high-quality childcare available

    Interested persons should submit the following documents:

    1) Single-page application letter. (Summary of scientific work and motivation for applying).
    2) Curriculum vitae (summarizing education, positions and other qualifying activity).
    3) List of publications.
    4) Contact information of two-three references that must include one coworker and supervisor (name, email address, affiliation, phone number and relation to the candidate).

    Applications must be submitted through the official recruitment website WebCruiter.