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Folkehelseinstituttet

Mass cytometry (CyTOF) in public health applications - Post Doc position available

Forskning og utvikling

One 3 year Post-doc position is available in the Division of Infection Control and Environmental Health. Our overall aim is to prevent infectious diseases and health impacts from biological, chemical and physical factors in the environment. We seek candidates interested in preventive medicine and public health – in the fields of infection control/vaccines and environmental medicine/toxicology. The position is closely linked to the newly established NIPH mass cytometry (CyTOF) platform, and include interdisciplinary collaboration with immunologists, toxicologists, epidemiologists, statisticians and technicians.

We are seeking a candidate for a new Post-doc position in the Department of Environmental Health. You will work with immunotoxicology and mass cytometry technology. The department of Environmental Health is focusing on the prevention of human health effects caused by chemicals and physical factors in the environment. The department is involved in hazard and risk assessment for national and international bodies. This work is supported by an extensive research portfolio mainly funded by NFR and the EU.

The section of Toxicology and Risk Assessment is a partner in two of the EU H2020 Exposome projects. In the EXIMIOUS project (https://www.eximious-h2020.eu) the effects of particles and chemicals on the immune system and the development of autoimmune disease will be studied. NIPH is work package leader for the immunomics part. By using our mass cytometry (CyTOF) platform we will study the effects of environmental exposures on innate and adaptive immune cells and their function in blood, both in human cohorts as well as in vitro. Our new post-doc will be central in generating this CyTOF data and in discussions in the EXIMIOUS consortium regarding the interpretation of the CyTOF results and integration of data on exposure, immunological and (epi)genetic findings.

The position is available from January 2021. 

A permanent Scientist position applying mass cytometry (CyTOF) is also available in the Division of Infection Control and Environmental Health, see advert 4292784007 in our recruitment portal: https://945000.webcruiter.no/Main/Recruit/Public/4292784007?language=en&link_source_id=0&showExpired=False

 

Main duties
  • Improve and develop protocols and participate in laboratory work related to mass cytometry (CyTOF) analysis of cohort and in vitro samples
  • Analyse CyTOF data in relation to environmental exposures by supervised and unsupervised data analysis tools
  • Develop in vitro approaches to study the effects of environmental exposures on the immune system
  • Publish papers and internal reports and present the results obtained on scientific conferences
  • Collaborate with other scientists and engineers in the department, the NIPH mass cytometry platform and with other institutes/universities of the EXIMIOUS consortium
  • Participate in consortium meetings and present project status and results
  • Contribute to discussions on the further development of the area of immunotoxicology at the institute 
Qualifications
  • Background and PhD degree from relevant fields, such as immunology, toxicology, pharmacology, or medicine
  • Hands-on laboratory experience with relevant methods
  • Experience with mass cytometry technology or other advanced immunological laboratory methods like high parameter flowcytometry is an advantage
  • Background within immunology and/or cellular physiology is highly beneficial
  • Interest for and experience with high-dimensional and high throughput analyses, and R competence, is an advantage
  • Relevant research experience with publications in international journals
  • Good English oral and written communication skills
  • When relevant: willingness to learn Norwegian 
Personal attributes
  • Strong collaboration skills, work capacity, social skills and a positive attitude is important
  • Highly motivated and strong problem solving skills
  • Structured, exact and result oriented work approach 
We offer
  • An interesting position in a European project with multiple opportunities to contribute with cutting edge science
  • Opportunity to shape the area of immunotoxicology at the institute and in an international context
  • Opportunity to translate data into knowledge that can be used in the regulation of chemicals
  • Interesting position in a multidisciplinary, engaged and competent research environment with focus on public health
  • Opportunity to further develop our mass cytometry technology platform
  • A multidisciplinary work environment within the department and institute with focus on and public health
  • Salary based on qualifications following the state regulations
  • Pension scheme in the Government Pension Fund
  • Flexible working hours
 

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