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Helse Sør-øst RHFSøknadsfrist
04.05.2023Heltid/Deltid
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0450, OSLO
OSLO
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1karriere-kode
5075434Se her for andre jobber fra Helse Sør-øst RHF
- Oppdatert 04.05.2023
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Helse Sør-øst RHF
PhD Research Fellow
Offentlig forvaltning
A 3-year position as PhD student is available at the Department of Medical Genetics, Oslo University Hospital. The position will be associated with the ‘breast cancer heterogeneity and oncoimmunology’ project group (https://www.ous-research.no/tekpli) and is financed by the Norwegian Health authorities through the project: "Spatial and longitudinal analyses of single cells in breast tumors to characterize and overcome resistance to therapies".
The lab has longstanding collaborations with oncologists at Oslo University Hospital (OUH) and Akershus University Hospital (Ahus) and conducts translational research in numerous clinical trials. Currently, through our collaborations with oncologists we have an ambitious new initiative aiming at merging the exciting new field of single-cell analysis with clinical studies.
The past 2-3 years, we have performed single cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) on tumor biopsies sampled at different time points of neoadjuvant therapy. Currently, the major focus of the lab is to use single cell technologies to understand which exact cell types /phenotypes are sensitive or resistant to therapies and to characterize how the tumor microenvironment determines tumor behavior and response to cancer therapies.
The Department of Medical Genetics at Oslo University Hospital is Norway’s largest medical genetics department with over 200 employees. The department is responsible for diagnostics of rare and inherited diseases, and runs a national research infrastructure for high-throughput DNA sequencing at the Norwegian Consortium for Sequencing and Personalized Medicine (www.norseq.org) . The research section in the department has 7 research groups (www.ous-research.no/meg/) working in various fields of medical genetics, including genetics, epigenetics, bioinformatics and functional genetics of breast cancer, autoimmune diseases, neurological, cardiovascular and psychiatricdisorders.
Oslo University Hospital is a workplace with great diversity. We believe this is absolutely crucial to solving the tasks required of us. We therefore want this diversity to be reflected among the applicants for our positions and encourage everyone to apply regardless of who you are and what background you have.Kvalifikasjoner:
We are looking for a highly motivated person, well organized and dynamic with creative thinking.
- The applicants must have a MSc with a topic in one of the following areas: bioinformatics, computational biology, molecular biology or similar.
- Working proficiency in appropriate programming languages and software. Advance knowledge in R and/or python.
- Experience in one of the following topics will be considered a plus: machine learning, analysis of scRNA-seq or ST data /knowledge of genomics /pathway biology/ (cancer) immunology /(statistical) data analysis.
- Ability to be inventive and to present novel ideas, data analyses and interpretation.
- Meet the requirements for admission to the faculty's doctoral program
Appointment to a PhD position requires that you are admitted to the PhD program within three months of employment, and that you participate in an organized PhD program during the employment period.
Personal skills
- The candidate should be able to work independently and interactively in a team setting, and also have large work capacity and enthusiasm for research
- High intrinsic motivation and scientific curiosity
- Proactive, flexible, and problem-solving attitude
- Excellent oral and written English communication skills.
- Personal skills will be emphasized
Personlige egenskaper:
- A full-time contract for three years with possibility for extension
- Salary in agreement with the current collective agreement
- A workplace that is an inclusive working life (IA) company
- Start date August 1st, 2023 (or upon agreement)
- Access to state-of-the-art technologies and HPC.
- A stimulating (international, multidisciplinary) research environment where quality, professionalism and team spirit are encouraged.
- A strong bioinformatic community gathered around the project such as being part of the European-Elixir single cell community and close collaboration with experienced computational biologists at the Norwegian Center of Molecular Medicine.
- The opportunity to be part of a young and dynamic team and to provide a meaningful contribution to genetic and oncological research.
- Rigorous research training and supervision
How to apply
All applications must include:
- A presentation letter describing your motivation for applying for the project and a PhD position
- A full CV (summarizing education, positions, academic work, scientific publications and other relevant activity)
- Transcripts and diplomas for bachelor's and master's degrees. (If you have not completed the master's degree, you must submit a confirmation that the master's thesis has been submitted).
- Copy of/link to master thesis and other scientific work you want us to consider
- Contact details of 2 referees (name, relation to candidate, e-mail and phone number)
Only applications thorugh Webcruiter will be considered.
Vi tilbyr:
Place of work
- The department is currently located at Ullevål, Oslo University hospital
- Excellent public transport in the town and a modern international airport with direct links to many cities throughout the world
Please don’t hesitate to contact us if you already have fulfilled a PhD and are very interested in our research, or if you have completed your MSc studies and not necessarily looking for a PhD position.
Bedrift
Helse Sør-øst RHFSøknadsfrist
04.05.2023Heltid/Deltid
HeltidAnsettelsesform
FastBransje
Offentlig forvaltningUtdanningskrav
PåkrevetArbeidserfaring
ØnskeligAdresse
0450, OSLO
OSLO
Antall stillinger
1karriere-kode
5075434Se her for andre jobber fra Helse Sør-øst RHF
- Oppdatert 04.05.2023