A PhD position in cancer immunology is available from September 2023 at the Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital.

We are seeking a suitable candidate for a 3-year PhD position for the project: TIME for CAR T in Norway; Role of Tumor Immune MicroEnvironment in CD19 CAR T-cell therapy. The project is funded by Norwegian Health Authorities and led by senior researcher Kanutte Huse. We will use the cutting-edge technology imaging mass cytometry to investigate biopsies from patients receiving CAR-T cell immunotherapy as part of clinical trials. The aim is to uncover resistance mechanisms to CAR-T cell therapy. Findings will be functionally validated in organoids and mouse models. The candidate will work in a team with other lab members and collaborators including bioinformaticians, experts in cell biology and immunology, clinicians and statisticians.

The position will be part of the Lymphoma Biology Group, headed by Associate Prof. June H. Myklebust. The Myklebust group is one of seven groups in the new Centre of Excellence, Precision Immunotherapy Alliance (PRIMA). We offer a dynamic and stimulating international scientific environment and a young, enthusiastic and motivated team with multidisciplinary expertise. Projects in the group span from basic to translational and preclinical cancer research. We study genomics and cellular composition in the tumor microenvironment to identify prognostic and predictive biomarkers. In addition, we aim to identify and target immunosuppressive cells that limit clinical responses to immunotherapy (https://ous-research.no/lymphomabiology/ ). The Institute for Cancer Research offers outstanding research facilities for translational cancer research, including modern laboratory space and hosts state-of-the-art core facilities for next-generation sequencing, flow/mass cytometry and imaging.  

Oslo University Hospital is a workplace with great diversity. We believe this is absolutely crucial to solving the tasks required of us. We therefore want this diversity to be reflected among the applicants for our positions and encourage everyone to apply regardless of who you are and what background you have.

Kvalifikasjoner:

• Master`s degree (MSc) in the field of immunology or molecular biology, or similar background
  
• Fulfill the requirements to be taken up by the UiO doctoral program
  
• Prior experience in cell culturing, multiparameter flow cytometry, immunohistochemistry, and/or bioinformatics will be an advantage, but not a necessity. Training will be provided.
  
• A FELASA C certificate in laboratory animal science or equivalent will be an advantage.

Personlige egenskaper:

• High working capacity
• Curiosity-driven with a strong motivation and capability to work in an organized manner
• Excellent teamwork skills and interest to work in a multidisciplinary team
• Good English written and oral communication skills

Vi tilbyr:

• Excellent working conditions
  
• An exciting and stimulating academic environment
  
• Focus on career development, with courses at the University of Oslo
  
• Highly attractive welfare benefits, and Oslo offers a family friendly environment and rich opportunity for culture and outdoor activities.
   

How to apply
The application with attachments must be submitted in our electronic recruiting system. All documents should be in English or a Scandinavian language.
 
The application must include:

• A one-page statement of motivation, summarizing scientific work and research interest
  
• CV (education and previous positions, and a list of laboratory techniques mastered)
  
• A complete list of publications and meeting abstracts
  
• Transcripts of University Diplomas
  
• Names and contact details for 2-3 references (name, relation to the candidate, email and phone number)
   
  In assessing the applications, special emphasis will be placed on the documented, academic qualifications, as well as the candidates’ motivation and personal suitability. Interviews with the best qualified candidates will be arranged.